MYOCARDIAL B CELLS HAVE SPECIFIC GENE EXPRESSION AND PREDICTED INTERACTIONS IN DILATED CARDIOMYOPATHY AND ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY

IntroductionGrowing evidence from animal models indicates that the myocardium hosts a population of B cells that play a role in the development of cardiomyopathy.However, there is minimal data on human myocardial B cells in the context of cardiomyopathy.MethodsWe integrated single-cell and single-nuclei datasets from 45 healthy human hearts, 70 hea

The cerebellum generates its vast amount of output to the cerebral cortex through the dentate nucleus (DN) that is essential for precise limb movements in primates.Nuclear cells in DN generate burst activity prior to limb movement, and inactivation of DN results in cerebellar ataxia.The question is how DN cells become active under intensive inhibit

A vast microbial community inhabits in the rhizosphere, among which, specialized bacteria known as Plant Growth-Promoting Rhizobacteria (PGPR) confer benefits to host plants including growth promotion and disease suppression.PGPR taxa vary in the ways whereby they curtail the negative effects of invading plant Canvas Wallet pathogens.However, a cum

Phoneutria nigriventer is one of the largest existing true spiders and one of the few considered medically relevant.Its venom contains several neurotoxic peptides that act on different ion channels and chemical receptors of vertebrates and invertebrates.Some of these venom toxins have been shown as promising models for pharmaceutical or biotechnolo

Background Arm Chairs The current behind armor blunt trauma (BABT) injury criterion uses a single penetration limit of 44 mm in Roma Plastilina clay and is not specific to thoracoabdominal regions.However, different regions in the human body have different injury tolerances.This manuscript presents a matched-pair hybrid test paradigm with different